On June 18 at 12:29 PM, the session "Systems Modeling in Single Cells: Consequences of Stochastic Expression" will take place in the EA2 amphitheater. The lecture will be delivered by Abhyudai Singh, a Full Professor at the University of Delaware.

About the speaker

Prof. Abhyudai Singh Singh has appointments in Electrical & Computer Engineering, Biomedical Engineering, and Mathematical Sciences. He holds degrees from IIT Kanpur, Michigan State University, and the University of California Santa Barbara, where he earned his PhD in Electrical & Computer Engineering. His research spans systems biology, virology, medicine, and neuroscience, focusing on modeling and inference in biomedical systems.

Abstract

Gene expression in cells is inherently stochastic, leading to significant cell-to-cell variability—even among genetically identical cells in the same environment. Understanding these fluctuations is critical to decoding how noise at the molecular level impacts biological function and phenotype.

This talk introduces computational frameworks for modeling stochastic gene regulatory networks, supported by experimental results. Applications include the emergence of transient drug-tolerant states in bacterial and cancer cells, and how stochastic protein expression shapes variability in lysis time and viral burst size in bacteriophage lambda.

Interested in Lunch?

If you would like lunch to be provided at the seminar, please fill out this form by May 30th at noon:
🔗 https://forms.gle/gmAX3uFPBXJeY32w5

Photo: University of Delaware